|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
negative regulation of cell proliferation
cellular response to stress
|
|
gptkbp:biologicalProcess
|
protein tyrosine/serine/threonine phosphatase activity
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
Dual specificity protein phosphatase 8 (protein)
|
|
gptkbp:Entrez_Gene_ID
|
1850
ENSG00000109906
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:kidney
gptkb:testis
brain
heart
|
|
gptkbp:fullName
|
gptkb:Dual_specificity_protein_phosphatase_8
|
|
gptkbp:function
|
dephosphorylates MAP kinases
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3072
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DUSP8
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
chromosome 11
|
|
gptkbp:OMIM
|
603117
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Dusp8
|
|
gptkbp:proteinFamily
|
gptkb:dual_specificity_phosphatases
|
|
gptkbp:regulates
|
gptkb:MAPK/ERK_pathway
gptkb:JNK_pathway
gptkb:p38_MAPK_pathway
|
|
gptkbp:UniProtID
|
gptkb:Q13202
|
|
gptkbp:bfsParent
|
gptkb:DUSP
|
|
gptkbp:bfsLayer
|
6
|