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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:JNK2
SAPK1a
|
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gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
inflammatory response
cellular response to stress
|
|
gptkbp:encodes
|
gptkb:Mitogen-activated_protein_kinase_9
|
|
gptkbp:Entrez_Gene_ID
|
5601
ENSG00000107643
|
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gptkbp:expressedIn
|
various tissues
|
|
gptkbp:firstDescribed
|
1994
|
|
gptkbp:function
|
regulates transcription
involved in apoptosis
involved in stress-activated protein kinase signaling pathway
involved in cellular proliferation
involved in differentiation
|
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gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasIsoform
|
multiple
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK9 gene
|
|
gptkbp:interactsWith
|
gptkb:ATF2
gptkb:Elk-1
gptkb:c-Jun
gptkb:MAP2K4
gptkb:MAP2K7
gptkb:JIP1
|
|
gptkbp:involves
|
gptkb:JNK_signaling_pathway
gptkb:MAPK_signaling_pathway
apoptosis pathway
|
|
gptkbp:length
|
424 amino acids
approximately 21 kb
|
|
gptkbp:locatedOnChromosome
|
gptkb:5q35.3
gptkb:chromosome_5
|
|
gptkbp:memberOf
|
gptkb:MAP_kinase_family
|
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gptkbp:molecularWeight
|
48 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
neurological disorders
|
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gptkbp:numberOfExons
|
13
|
|
gptkbp:OMIM
|
602448
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Mapk9
|
|
gptkbp:phosphorylates
|
gptkb:ATF2
gptkb:Elk-1
gptkb:c-Jun
|
|
gptkbp:product
|
JNK2 protein
|
|
gptkbp:referenceGenome
|
NM_002753
|
|
gptkbp:regulates
|
activated by dual phosphorylation on threonine and tyrosine residues
|
|
gptkbp:UniProtID
|
gptkb:P45983
|
|
gptkbp:bfsParent
|
gptkb:MAPK9
gptkb:JNK2
|
|
gptkbp:bfsLayer
|
7
|