|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:ERK1
gptkb:Mitogen-activated_protein_kinase_3
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Noonan_syndrome
cardiomyopathy
|
|
gptkbp:biologicalProcess
|
protein kinase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:encodedBy
|
gptkb:MAPK3_gene
|
|
gptkbp:Entrez_Gene_ID
|
5595
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.24
|
|
gptkbp:family
|
gptkb:MAP_kinase_family
|
|
gptkbp:function
|
signal transduction
regulation of cell proliferation
regulation of transcription
regulation of differentiation
|
|
gptkbp:GO_term
|
GO:0005524
GO:0000165
GO:0004672
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK3 protein
|
|
gptkbp:interactsWith
|
gptkb:MAP2K1
gptkb:ELK1
gptkb:MAP2K2
gptkb:DUSP6
|
|
gptkbp:length
|
379 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p11.2
|
|
gptkbp:molecularWeight
|
43 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Mapk3
|
|
gptkbp:pathway
|
gptkb:MAPK/ERK_pathway
|
|
gptkbp:PDB
|
2ZOQ
4QTB
6GES
|
|
gptkbp:phosphorylates
|
threonine 202
tyrosine 204
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:reviewedBy
|
gptkb:NCBI_Gene
gptkb:UniProt
gptkb:Ensembl
gptkb:Reactome
|
|
gptkbp:subfamily
|
gptkb:ERK_subfamily
|
|
gptkbp:subunit
|
dimer
monomer
|
|
gptkbp:UniProtID
|
gptkb:P27361
|
|
gptkbp:bfsParent
|
gptkb:MAPK3_gene
|
|
gptkbp:bfsLayer
|
7
|