|
gptkbp:instanceOf
|
gptkb:drug
antidepressant
monoamine oxidase inhibitor
|
|
gptkbp:ATCCode
|
N06AF04
|
|
gptkbp:brand
|
gptkb:Parnate
|
|
gptkbp:CASNumber
|
13492-01-8
|
|
gptkbp:category
|
amphetamine
cyclopropane derivative
|
|
gptkbp:chemicalFormula
|
C9H11N
|
|
gptkbp:contraindication
|
gptkb:pheochromocytoma
congestive heart failure
cerebrovascular disease
|
|
gptkbp:discoveredBy
|
gptkb:Smith,_Kline_&_French
|
|
gptkbp:eliminationHalfLife
|
2.5 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasInChIKey
|
DZGWFCBHGJWVFI-UHFFFAOYSA-N
|
|
gptkbp:hasSMILES
|
c1ccc(cc1)C2CC2N
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
tranylcypromine
|
|
gptkbp:interactsWith
|
gptkb:SSRIs
gptkb:TCAs
gptkb:sympathomimetics
tyramine-containing foods
|
|
gptkbp:introducedIn
|
1961
|
|
gptkbp:IUPACName
|
gptkb:(±)-trans-2-phenylcyclopropan-1-amine
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
irreversible inhibitor of monoamine oxidase
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
133.19 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1082
gptkb:DB00752
60954
54913
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
dizziness
insomnia
dry mouth
hypertensive crisis
|
|
gptkbp:UNII
|
6R9Y6R3D9F
|
|
gptkbp:usedFor
|
gptkb:major_depressive_disorder
treatment-resistant depression
atypical depression
|
|
gptkbp:bfsParent
|
gptkb:monoamine_oxidase_inhibitors
gptkb:CYP2A6
gptkb:MAO_inhibitors
|
|
gptkbp:bfsLayer
|
6
|