Lymphocyte-specific protein tyrosine kinase

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:enzyme
gptkbp:alternativeName	p56lck LCK proto-oncogene, Src family tyrosine kinase
gptkbp:belongs_to_protein_family	gptkb:Src_family_kinases
gptkbp:biologicalProcess	gptkb:T_cell_receptor_signaling_pathway gptkb:immune_response protein tyrosine kinase activity
gptkbp:cellularComponent	gptkb:nucleus gptkb:cytoplasm gptkb:plasma_membrane
gptkbp:enzymeCommissionNumber	2.7.10.2
gptkbp:expressedIn	gptkb:natural_killer_cells T lymphocytes
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	signal transduction T cell activation
gptkbp:gene	gptkb:LCK
gptkbp:interactsWith	gptkb:T_cell_receptor_complex gptkb:CD4 gptkb:CD8
gptkbp:locatedOnChromosome	gptkb:chromosome_1q32
gptkbp:molecularWeight	56 kDa
gptkbp:PDB	gptkb:3LCK
gptkbp:phosphorylates	gptkb:ZAP-70 gptkb:CD3_zeta_chain
gptkbp:regulates	regulated by phosphorylation
gptkbp:significance	implicated in leukemia
gptkbp:UniProtID	P06239
gptkbp:bfsParent	gptkb:P06276 gptkb:Lck
gptkbp:bfsLayer	8
http://www.w3.org/2000/01/rdf-schema#label	Lymphocyte-specific protein tyrosine kinase