|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
CD85d
ILT4
LIR-2
MIR10
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
autoimmune diseases
|
|
gptkbp:cellSurfaceMarker
|
yes
|
|
gptkbp:discoveredBy
|
1997
|
|
gptkbp:domain
|
immunoglobulin-like domains
ITIM motifs
|
|
gptkbp:downstream_effector
|
gptkb:SHP-2
gptkb:SHP-1
|
|
gptkbp:Entrez_Gene_ID
|
10289
ENSG00000151006
|
|
gptkbp:expressedIn
|
gptkb:NK_cells
gptkb:B_cells
gptkb:placenta
dendritic cells
macrophages
monocytes
peripheral blood leukocytes
|
|
gptkbp:fullName
|
Leukocyte immunoglobulin-like receptor subfamily B member 2
|
|
gptkbp:function
|
binds MHC class I molecules
inhibitory receptor on immune cells
|
|
gptkbp:HGNC_ID
|
gptkb:LILRB2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LILRB2
|
|
gptkbp:inhibitedBy
|
activation of immune cells
|
|
gptkbp:inhibitory_signal
|
ITIM phosphorylation
|
|
gptkbp:interactsWith
|
gptkb:HLA_class_I_molecules
gptkb:HLA-A
gptkb:HLA-B
gptkb:HLA-C
gptkb:HLA-E
gptkb:HLA-F
gptkb:HLA-G
|
|
gptkbp:locatedOnChromosome
|
19
|
|
gptkbp:location
|
19q13.4
|
|
gptkbp:molecularWeight
|
~65 kDa
|
|
gptkbp:numberOfExons
|
10
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Lilrb2
|
|
gptkbp:proteinFamily
|
type I transmembrane glycoprotein
leukocyte immunoglobulin-like receptor family
|
|
gptkbp:regulates
|
immune response
|
|
gptkbp:transmembraneDomains
|
yes
|
|
gptkbp:UniProtID
|
Q8N423
|
|
gptkbp:bfsParent
|
gptkb:LILR
|
|
gptkbp:bfsLayer
|
7
|