Statements (32)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alsoKnownAs |
gptkb:KRAS
|
gptkbp:associatedWith |
gptkb:cancer
|
gptkbp:discoveredBy |
gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop |
gptkbp:encodes |
gptkb:KRAS_protein
|
gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000133703
3845 |
gptkbp:expressedIn |
many tissues
|
gptkbp:firstDescribed |
1982
|
gptkbp:function |
guanine nucleotide exchange factor
|
gptkbp:HGNC_ID |
6407
|
https://www.w3.org/2000/01/rdf-schema#label |
Ki-ras
|
gptkbp:involvedIn |
gptkb:PI3K-AKT_signaling_pathway
gptkb:MAPK_signaling_pathway |
gptkbp:locatedOnChromosome |
12p12.1
|
gptkbp:memberOf |
gptkb:RAS_gene_family
|
gptkbp:mutationAssociatedWith |
gptkb:cancer
colorectal cancer oncogenic pancreatic cancer |
gptkbp:OMIM |
190070
|
gptkbp:orthologInMouse |
gptkb:Kras
|
gptkbp:product |
gptkb:KRAS_protein
|
gptkbp:regulates |
cell differentiation
cell proliferation cell survival |
gptkbp:species |
gptkb:Homo_sapiens
|
gptkbp:target |
anticancer drugs
|
gptkbp:UniProtID |
gptkb:P01116
|
gptkbp:bfsParent |
gptkb:KRAS
|
gptkbp:bfsLayer |
5
|