|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:SCF
gptkb:mast_cell_growth_factor
gptkb:steel_factor
gptkb:stem_cell_factor
|
|
gptkbp:alternativeSplicing
|
multiple isoforms
|
|
gptkbp:associatedWith
|
gptkb:familial_progressive_hyperpigmentation
gptkb:piebaldism
testicular germ cell tumor
|
|
gptkbp:discoveredBy
|
Doolittle et al.
|
|
gptkbp:encodes
|
gptkb:KIT_ligand_protein
|
|
gptkbp:Entrez_Gene_ID
|
4254
ENSG00000157404
|
|
gptkbp:expressedIn
|
gptkb:skin
gptkb:testis
bone marrow
|
|
gptkbp:firstDescribed
|
1990
|
|
gptkbp:function
|
melanogenesis
regulation of hematopoiesis
gametogenesis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:6342
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KITLG gene
|
|
gptkbp:interactsWith
|
KIT receptor
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12
12q21.32
|
|
gptkbp:mutationAssociatedWith
|
gptkb:piebaldism
cancer susceptibility
|
|
gptkbp:OMIM
|
184745
|
|
gptkbp:orthologInMouse
|
gptkb:Kitlg
gptkb:Kitl
|
|
gptkbp:orthologInZebrafish
|
kitlga
kitlgb
|
|
gptkbp:pathway
|
gptkb:Hematopoietic_cell_lineage
gptkb:Melanogenesis
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
Stem cell factor signaling
|
|
gptkbp:product
|
gptkb:KIT_ligand
|
|
gptkbp:proteinFamily
|
cytokine family
|
|
gptkbp:regulates
|
gptkb:GATA2
gptkb:MITF
gptkb:SOX10
cell differentiation
cell proliferation
cell survival
cell migration
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
P21583
|
|
gptkbp:bfsParent
|
gptkb:Stem_Cell_Factor
gptkb:stem_cell_factor
|
|
gptkbp:bfsLayer
|
7
|