Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:affects |
genetic factors
environmental factors hormonal factors |
| gptkbp:dysfunction_causes |
gptkb:melasma
albinism vitiligo |
| https://www.w3.org/2000/01/rdf-schema#label |
Melanogenesis
|
| gptkbp:importantFor |
protection against UV radiation
|
| gptkbp:influenced |
gptkb:alpha-MSH
gptkb:ACTH gptkb:endothelin-1 gptkb:stem_cell_factor nitric oxide inflammatory cytokines |
| gptkbp:involves |
dopaquinone formation
eumelanin synthesis oxidation of tyrosine pheomelanin synthesis production of melanin |
| gptkbp:occurredIn |
gptkb:melanocytes
epidermis hair follicles |
| gptkbp:regulates |
gptkb:MC1R
gptkb:MITF gptkb:tyrosinase UV radiation |
| gptkbp:result |
hair pigmentation
skin pigmentation eye pigmentation |
| gptkbp:bfsParent |
gptkb:KITLG
gptkb:KITLG_gene |
| gptkbp:bfsLayer |
8
|