Statements (33)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:biological_pathway
                                        
                                         | 
                            
| gptkbp:affects | 
                                    
                                        
                                            
                                            genetic factors
                                        
                                        
                                         environmental factors hormonal factors  | 
                            
| gptkbp:dysfunction_causes | 
                                    
                                        
                                            gptkb:melasma
                                        
                                         albinism vitiligo  | 
                            
| gptkbp:importantFor | 
                                    
                                        
                                            
                                            protection against UV radiation
                                        
                                        
                                         | 
                            
| gptkbp:influenced | 
                                    
                                        
                                            gptkb:alpha-MSH
                                        
                                         gptkb:ACTH gptkb:endothelin-1 gptkb:stem_cell_factor nitric oxide inflammatory cytokines  | 
                            
| gptkbp:involves | 
                                    
                                        
                                            
                                            dopaquinone formation
                                        
                                        
                                         eumelanin synthesis oxidation of tyrosine pheomelanin synthesis production of melanin  | 
                            
| gptkbp:occurredIn | 
                                    
                                        
                                            gptkb:melanocytes
                                        
                                         epidermis hair follicles  | 
                            
| gptkbp:regulates | 
                                    
                                        
                                            gptkb:MC1R
                                        
                                         gptkb:MITF gptkb:tyrosinase UV radiation  | 
                            
| gptkbp:result | 
                                    
                                        
                                            
                                            hair pigmentation
                                        
                                        
                                         skin pigmentation eye pigmentation  | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:KITLG
                                        
                                         gptkb:KITLG_gene  | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            8
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            Melanogenesis
                                        
                                        
                                         |