Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:VEGFR-2
gptkb:Flk-1 |
| gptkbp:discoveredBy |
Terman et al.
|
| gptkbp:discoveredIn |
1991
|
| gptkbp:encodes |
vascular endothelial growth factor receptor 2
|
| gptkbp:Entrez_Gene_ID |
3791
ENSG00000128052 |
| gptkbp:expressedIn |
endothelial cells
|
| gptkbp:fullName |
kinase insert domain receptor
|
| gptkbp:function |
gptkb:receptor_tyrosine_kinase
regulates angiogenesis mediates VEGF-induced endothelial proliferation |
| gptkbp:HGNC_ID |
HGNC:6307
|
| gptkbp:locatedOnChromosome |
4q12
|
| gptkbp:memberOf |
protein tyrosine kinase family
VEGF receptor family |
| gptkbp:mutationAssociatedWith |
gptkb:cancer
pre-eclampsia |
| gptkbp:OMIM |
191306
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Flk1
|
| gptkbp:targetOfDrug |
gptkb:sorafenib
gptkb:pazopanib gptkb:regorafenib gptkb:sunitinib gptkb:axitinib gptkb:ramucirumab |
| gptkbp:UniProtID |
P35968
|
| gptkbp:bfsParent |
gptkb:VEGFR
gptkb:Qandahar gptkb:VEGFR2 |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
KDR
|