Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:JAK-STAT_signaling_pathway
|
| gptkbp:discoveredBy |
Ian Wilks
|
| gptkbp:domain |
kinase domain
SH2 domain pseudokinase domain Ferm domain |
| gptkbp:foundIn |
vertebrates
|
| gptkbp:fullName |
gptkb:Janus_kinases
|
| gptkbp:function |
intracellular non-receptor tyrosine kinases
|
| https://www.w3.org/2000/01/rdf-schema#label |
JAKs
|
| gptkbp:involvedIn |
cytokine receptor signaling
|
| gptkbp:member |
gptkb:JAK2
gptkb:JAK1 gptkb:TYK2 gptkb:JAK3 |
| gptkbp:mutationAssociatedWith |
immunodeficiency
myeloproliferative disorders |
| gptkbp:namedAfter |
Roman god Janus
|
| gptkbp:phosphorylates |
gptkb:STAT_proteins
|
| gptkbp:target |
JAK inhibitors
|
| gptkbp:bfsParent |
gptkb:STATs
|
| gptkbp:bfsLayer |
7
|