ILK (integrin-linked kinase)
GPTKB entity
Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
ILK1
Integrin-linked protein kinase p59ILK |
| gptkbp:associatedWith |
gptkb:cancer
cardiomyopathy |
| gptkbp:biologicalProcess |
cell proliferation
signal transduction ATP binding apoptosis regulation protein kinase activity regulation of cell shape cell-matrix adhesion |
| gptkbp:discoveredBy |
1996
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
cell survival
signal transduction cell migration cell adhesion regulation of cytoskeleton |
| gptkbp:gene |
ILK
ILK gene |
| https://www.w3.org/2000/01/rdf-schema#label |
ILK (integrin-linked kinase)
|
| gptkbp:inhibitedBy |
Cpd22
QLT0267 |
| gptkbp:interactsWith |
gptkb:AKT1
gptkb:integrins gptkb:talin gptkb:Paxillin PINCH alpha-parvin beta-parvin parvin |
| gptkbp:locatedIn |
gptkb:cytoplasm
focal adhesions |
| gptkbp:locatedOnChromosome |
11p15.4
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:part_of_complex |
ILK-PINCH-parvin complex
|
| gptkbp:phosphorylates |
gptkb:AKT1
gptkb:GSK3B |
| gptkbp:regulates |
cell cycle
actin cytoskeleton cell motility integrin signaling cell survival pathways |
| gptkbp:structure |
contains kinase domain
contains ankyrin repeats |
| gptkbp:UniProtID |
Q13418
|
| gptkbp:bfsParent |
gptkb:FERMT2
|
| gptkbp:bfsLayer |
8
|