Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cytokine |
| gptkbp:alternativeName |
gptkb:CXCL8
gptkb:IL-8 |
| gptkbp:discoveredIn |
1987
|
| gptkbp:encodedBy |
gptkb:CXCL8_gene
|
| gptkbp:function |
inflammatory response
chemotaxis of neutrophils |
| https://www.w3.org/2000/01/rdf-schema#label |
Human protein Interleukin-8
|
| gptkbp:involvedIn |
immune response
acute inflammation |
| gptkbp:locatedOnChromosome |
4q13-q21
|
| gptkbp:molecularWeight |
8 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:postTranslationalModification |
N-terminal truncation
|
| gptkbp:producedBy |
macrophages
endothelial cells epithelial cells |
| gptkbp:promotion |
gptkb:IL-1
gptkb:TNF-alpha bacterial products |
| gptkbp:recipient |
gptkb:CXCR2
gptkb:CXCR1 |
| gptkbp:sequence |
99 amino acids
|
| gptkbp:significance |
implicated in cancer progression
marker for inflammation implicated in chronic obstructive pulmonary disease implicated in cystic fibrosis |
| gptkbp:structure |
dimer
monomer |
| gptkbp:UniProtID |
P10145
|
| gptkbp:bfsParent |
gptkb:P15391
|
| gptkbp:bfsLayer |
7
|