Human protein Interleukin-8

URI: https://gptkb.org/entity/Human_protein_Interleukin-8
GPTKB entity
Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:cytokine
gptkb:protein
gptkbp:alternativeName gptkb:CXCL8
gptkb:IL-8
gptkbp:discoveredIn 1987
gptkbp:encodedBy gptkb:CXCL8_gene
gptkbp:function inflammatory response
chemotaxis of neutrophils
gptkbp:involvedIn gptkb:immune_response
acute inflammation
gptkbp:locatedOnChromosome 4q13-q21
gptkbp:molecularWeight 8 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:postTranslationalModification N-terminal truncation
gptkbp:producedBy macrophages
endothelial cells
epithelial cells
gptkbp:promotion gptkb:IL-1
gptkb:TNF-alpha
bacterial products
gptkbp:recipient gptkb:CXCR2
gptkb:CXCR1
gptkbp:sequence 99 amino acids
gptkbp:significance implicated in cancer progression
marker for inflammation
implicated in chronic obstructive pulmonary disease
implicated in cystic fibrosis
gptkbp:structure gptkb:monomer
dimer
gptkbp:UniProtID P10145
gptkbp:bfsParent gptkb:P15391
gptkb:P20936
gptkb:P15382
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label Human protein Interleukin-8