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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:IL8
NAP-1
interleukin 8
neutrophil-activating protein 1
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
inflammation
|
|
gptkbp:discoveredBy
|
Yoshimura et al.
|
|
gptkbp:discoveredIn
|
1987
|
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gptkbp:encodes
|
gptkb:interleukin-8
|
|
gptkbp:Entrez_Gene_ID
|
3576
ENSG00000169429
|
|
gptkbp:expressedIn
|
endothelial cells
immune cells
epithelial cells
|
|
gptkbp:function
|
inflammatory response
chemotaxis
neutrophil activation
|
|
gptkbp:GO_term
|
gptkb:GO:0008009_(chemokine_activity)
GO:0006954 (inflammatory response)
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
6025
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CXCL8 gene
|
|
gptkbp:length
|
4 exons
|
|
gptkbp:locatedOnChromosome
|
4q13-q21
|
|
gptkbp:OMIM
|
146930
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Cxcl15
|
|
gptkbp:product
|
gptkb:IL-8
|
|
gptkbp:proteinFamily
|
CXC chemokine family
|
|
gptkbp:regulates
|
regulated by NF-kB
induced by pro-inflammatory cytokines
|
|
gptkbp:UniProtID
|
P10145
|
|
gptkbp:bfsParent
|
gptkb:interleukin-8
|
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gptkbp:bfsLayer
|
7
|