Hematopoietic progenitor kinase 1
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:HPK1
gptkb:MAP4K1 |
| gptkbp:enzymeCommissionNumber |
2.7.11.25
|
| gptkbp:expressedIn |
hematopoietic cells
lymphoid tissues |
| gptkbp:function |
signal transduction
serine/threonine kinase |
| gptkbp:gene |
gptkb:HPK1
gptkb:MAP4K1 |
| https://www.w3.org/2000/01/rdf-schema#label |
Hematopoietic progenitor kinase 1
|
| gptkbp:inhibitedBy |
NF-kappaB signaling
|
| gptkbp:interactsWith |
gptkb:14-3-3_proteins
gptkb:GRB2 CARMA1 |
| gptkbp:involves |
gptkb:T_cell_receptor_signaling_pathway
immune response |
| gptkbp:locatedOnChromosome |
19q13.1
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
97 kDa
|
| gptkbp:OMIM |
604552
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
2HJN
|
| gptkbp:phosphorylates |
gptkb:NFAT
gptkb:JNK |
| gptkbp:regulates |
apoptosis
cell proliferation T cell activation B cell receptor signaling |
| gptkbp:UniProtID |
Q92918
|
| gptkbp:bfsParent |
gptkb:HPK1
|
| gptkbp:bfsLayer |
8
|