|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:p21ras
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
cell survival
signal transduction
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:enzymeClassification
|
gptkb:EC_3.6.5.2
|
|
gptkbp:family
|
gptkb:Ras_family
|
|
gptkbp:form
|
GTP-bound
|
|
gptkbp:function
|
guanine nucleotide exchange factor
|
|
gptkbp:gene
|
gptkb:HRAS
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HRas protein (rat)
|
|
gptkbp:inactive_form
|
GDP-bound
|
|
gptkbp:interactsWith
|
gptkb:GAPs
gptkb:PI3K
gptkb:RAF1
gptkb:SOS1
|
|
gptkbp:locatedOnChromosome
|
chromosome 1 (rat)
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
oncogenic transformation
|
|
gptkbp:organism
|
gptkb:Rattus_norvegicus
|
|
gptkbp:orthologIn
|
HRas protein (human)
HRas protein (mouse)
|
|
gptkbp:pathway
|
gptkb:MAPK/ERK_pathway
gptkb:PI3K/AKT_pathway
|
|
gptkbp:PDB
|
gptkb:5P21
|
|
gptkbp:postTranslationalModification
|
farnesylation
palmitoylation
|
|
gptkbp:sequence
|
189 amino acids
|
|
gptkbp:structure
|
gptkb:G-domain
switch I region
switch II region
|
|
gptkbp:UniProtID
|
P08659
|
|
gptkbp:bfsParent
|
gptkb:HRAS_(rat)
|
|
gptkbp:bfsLayer
|
7
|