|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BZS
gptkb:MHAM
gptkb:MMAC1
gptkb:PTEN1
gptkb:TEP1
gptkb:CWS1
|
|
gptkbp:approvalYear
|
1997
|
|
gptkbp:approvedBy
|
gptkb:phosphatase_and_tensin_homolog
|
|
gptkbp:approvedSymbol
|
gptkb:PTEN
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bannayan-Riley-Ruvalcaba_syndrome
gptkb:Cowden_syndrome
gptkb:Lhermitte-Duclos_disease
gptkb:endometrial_cancer
gptkb:glioblastoma
gptkb:macrocephaly-autism_syndrome
melanoma
prostate cancer
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000171862
5728
|
|
gptkbp:essentialGene
|
yes
|
|
gptkbp:function
|
gptkb:protein
tumor suppressor
lipid phosphatase
|
|
gptkbp:geneGroup
|
Dual-specificity phosphatases
Tumor suppressor genes
|
|
gptkbp:hasPseudogene
|
gptkb:PTENP1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HGNC:9817
|
|
gptkbp:isHousekeepingGene
|
no
|
|
gptkbp:isImprinted
|
no
|
|
gptkbp:isLocatedOnStrand
|
minus
|
|
gptkbp:isOncogene
|
no
|
|
gptkbp:isTumorSuppressorGene
|
yes
|
|
gptkbp:length
|
403 amino acids
|
|
gptkbp:locatedOnChromosome
|
10
|
|
gptkbp:location
|
gptkb:10q23.31
|
|
gptkbp:locusType
|
gptkb:gene
|
|
gptkbp:OMIM
|
601728
|
|
gptkbp:orthologIn
|
gptkb:rat:Pten
mouse:Pten
|
|
gptkbp:previousName
|
gptkb:TGF-beta-regulated_and_epithelial_cell-enriched_phosphatase_1
gptkb:mutated_in_multiple_advanced_cancers_1
|
|
gptkbp:previousSymbols
|
gptkb:MMAC1
gptkb:TEP1
|
|
gptkbp:proteinFamily
|
phosphatases
|
|
gptkbp:RefSeq
|
gptkb:NM_000314
|
|
gptkbp:symbol
|
approved
|
|
gptkbp:UniProtID
|
gptkb:P60484
|
|
gptkbp:bfsParent
|
gptkb:RAD21
|
|
gptkbp:bfsLayer
|
6
|