|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:NXP-1
gptkb:SCC1_homolog
hHR21
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Cornelia_de_Lange_syndrome
cohesinopathies
|
|
gptkbp:cleavage
|
gptkb:Separase
|
|
gptkbp:cleavedDuring
|
anaphase
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
gptkb:Double-strand-break_repair_protein_rad21_homolog
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000164754
5885
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:function
|
DNA repair
regulation of gene expression
cohesin complex component
sister chromatid cohesion
|
|
gptkbp:geneLocationEnd
|
118,012,000
|
|
gptkbp:geneLocationStart
|
117,965,001
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:9817
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RAD21
|
|
gptkbp:interactsWith
|
gptkb:PDS5A
gptkb:SMC1A
gptkb:SMC3
gptkb:STAG2
gptkb:WAPL
|
|
gptkbp:length
|
631
|
|
gptkbp:locatedOnChromosome
|
gptkb:8q24.11
|
|
gptkbp:molecularWeight
|
~72 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:acute_myeloid_leukemia
cohesinopathies
|
|
gptkbp:OMIM
|
606462
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Saccharomyces_cerevisiae_(Scc1)
|
|
gptkbp:PDB
|
6H8Q
|
|
gptkbp:phosphorylates
|
Serine 175
Serine 282
|
|
gptkbp:regulates
|
chromosome segregation
transcriptional regulation
DNA double-strand break repair
|
|
gptkbp:reviewedBy
|
gptkb:GeneCards
gptkb:OMIM
gptkb:UniProt
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:O60216
|
|
gptkbp:bfsParent
|
gptkb:APRIN
|
|
gptkbp:bfsLayer
|
5
|