Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:HDAC3
RPD3-2 |
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases |
| gptkbp:EC_number |
3.5.1.98
|
| gptkbp:encodedBy |
gptkb:HDAC3_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of gene expression
removal of acetyl groups from histone proteins |
| https://www.w3.org/2000/01/rdf-schema#label |
Histone deacetylase 3
|
| gptkbp:inhibitedBy |
gptkb:trichostatin_A
gptkb:vorinostat |
| gptkbp:interactsWith |
NCoR complex
SMRT complex |
| gptkbp:locatedOnChromosome |
19q13.2
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:memberOf |
histone deacetylase family
|
| gptkbp:molecularWeight |
48 kDa
|
| gptkbp:postTranslationalModification |
phosphorylation
acetylation |
| gptkbp:regulates |
chromatin structure
transcriptional repression |
| gptkbp:UniProtID |
gptkb:O15379
|
| gptkbp:bfsParent |
gptkb:HDAC3
|
| gptkbp:bfsLayer |
7
|