HBEGF gene

GPTKB entity

Statements (48)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias gptkb:HBEGF
DTR
HEGFL
Hbegf
gptkbp:associatedWith gptkb:cancer
myocardial infarction
pre-eclampsia
gptkbp:biologicalProcess cell proliferation
wound healing
angiogenesis
growth factor activity
gptkbp:cellularComponent gptkb:plasma_membrane
extracellular region
gptkbp:discoveredBy gptkb:Higashiyama_et_al.
gptkbp:discoveredIn 1991
gptkbp:encodes heparin-binding EGF-like growth factor protein
gptkbp:Entrez_Gene_ID 1839
ENSG00000142959
GC05P140
gptkbp:expressedIn gptkb:cancer
gptkb:kidney
gptkb:placenta
heart
vascular smooth muscle cells
gptkbp:fullName gptkb:heparin-binding_EGF-like_growth_factor
gptkbp:function cell proliferation
wound healing
angiogenesis
growth factor activity
receptor binding
gptkbp:HGNC_ID 4838
gptkbp:interactsWith gptkb:EGFR
gptkb:ERBB4
gptkbp:length 6 exons
gptkbp:locatedOnChromosome gptkb:chromosome_5
5q31-q32
gptkbp:OMIM 126150
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Hbegf
gptkbp:postTranslationalModification glycosylation
proteolytic cleavage
gptkbp:proteinFamily gptkb:EGF_family
gptkbp:RefSeq NM_001945
gptkbp:UniProtID Q99075
gptkbp:bfsParent gptkb:HB-EGF
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label HBEGF gene