|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:epidermal_growth_factor_family
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
embryonic development
wound healing
|
|
gptkbp:contains
|
gptkb:amphiregulin
gptkb:betacellulin
gptkb:epidermal_growth_factor_(EGF)
gptkb:epiregulin
gptkb:transforming_growth_factor_alpha_(TGF-α)
gptkb:heparin-binding_EGF-like_growth_factor_(HB-EGF)
cryptic
neuregulins
epigen
cripto
schwannomin-interacting protein 1 (SCHIP1)
tomoregulin
|
|
gptkbp:discoveredBy
|
gptkb:Stanley_Cohen
|
|
gptkbp:discoveredIn
|
1962
|
|
gptkbp:domain
|
EGF-like domain
|
|
gptkbp:foundIn
|
animals
humans
mammals
|
|
gptkbp:function
|
cell signaling
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
EGF family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
developmental disorders
|
|
gptkbp:recipient
|
EGF receptor (EGFR)
ErbB2
ErbB3
ErbB4
|
|
gptkbp:relatedTo
|
gptkb:receptor_tyrosine_kinases
signal transduction
growth factors
|
|
gptkbp:structure
|
cysteine-rich domain
disulfide bonds
|
|
gptkbp:bfsParent
|
gptkb:HB-EGF
gptkb:TGF-alpha
gptkb:EGVF
gptkb:heparin-binding_EGF-like_growth_factor
|
|
gptkbp:bfsLayer
|
7
|