Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:GSK-3
|
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
gptkb:diabetes_mellitus bipolar disorder |
| gptkbp:biologicalProcess |
serine/threonine kinase activity
|
| gptkbp:cellularComponent |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:discoveredBy |
gptkb:D._Rylatt
|
| gptkbp:discoveredIn |
1980
|
| gptkbp:EC_number |
2.7.11.26
|
| gptkbp:encodedBy |
gptkb:GSK3A_gene
gptkb:GSK3B_gene |
| gptkbp:function |
involved in Wnt signaling pathway
involved in apoptosis involved in cell proliferation involved in insulin signaling pathway phosphorylates glycogen synthase regulates glycogen metabolism |
| gptkbp:hasIsoform |
gptkb:GSK-3α
gptkb:GSK-3β |
| https://www.w3.org/2000/01/rdf-schema#label |
Glycogen synthase kinase 3
|
| gptkbp:inhibitedBy |
gptkb:SB-216763
gptkb:CHIR99021 lithium |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
gptkb:P49840
gptkb:P49841 |
| gptkbp:bfsParent |
gptkb:GSK3
|
| gptkbp:bfsLayer |
6
|