Statements (22)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:chemical_compound
|
gptkbp:CASNumber |
252917-06-9
|
gptkbp:combines |
gptkb:PD0325901
gptkb:LIF |
gptkbp:hasMolecularFormula |
C22H18N8
|
gptkbp:hasSMILES |
C1=CC=C(C=C1)NC2=C(N(C(=O)N(C2=O)C)CNCCNCC3=CC(=NC=C3)C#N)N
|
gptkbp:heldBy |
ATP-competitive inhibitor
|
https://www.w3.org/2000/01/rdf-schema#label |
CHIR99021
|
gptkbp:inhibitedBy |
gptkb:GSK-3
|
gptkbp:is_selective_for |
gptkb:GSK-3α
gptkb:GSK-3β |
gptkbp:IUPACName |
6-[[2-[(4-Anilino-1,4-dihydro-1-methyl-2,6-dioxo-5-pyrimidinyl)methyl]amino]ethyl]amino]-3-pyridinecarbonitrile
|
gptkbp:molecularWeight |
382.43 g/mol
|
gptkbp:PubChem_CID |
gptkb:CHEMBL361276
10389219 |
gptkbp:used_in |
stem cell research
cell signaling studies Wnt signaling pathway studies induce pluripotency promote self-renewal of embryonic stem cells |
gptkbp:bfsParent |
gptkb:FX-322
|
gptkbp:bfsLayer |
5
|