|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:GSK3B_gene
bipolar disorder
|
|
gptkbp:biologicalProcess
|
apoptosis
cell differentiation
cell proliferation
kinase activity
ATP binding
protein binding
|
|
gptkbp:discoveredBy
|
1990s
|
|
gptkbp:encodes
|
gptkb:glycogen_synthase_kinase_3_alpha
|
|
gptkbp:Entrez_Gene_ID
|
2931
ENSG00000105723
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
liver
|
|
gptkbp:function
|
protein serine/threonine kinase activity
|
|
gptkbp:HGNC_ID
|
4617
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GSK3A gene
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
glycogen metabolism
insulin signaling pathway
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
19q13.2
|
|
gptkbp:OMIM
|
606784
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Gsk3a
|
|
gptkbp:product
|
gptkb:GSK3A_protein
|
|
gptkbp:RefSeq
|
NM_019884
|
|
gptkbp:regulates
|
activated by phosphorylation
inhibited by insulin
|
|
gptkbp:UniProtID
|
gptkb:P49840
|
|
gptkbp:bfsParent
|
gptkb:GSK3α
gptkb:Glycogen_synthase_kinase_3
|
|
gptkbp:bfsLayer
|
7
|