|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:activatedBy
|
gptkb:Factor_IXa
gptkb:Factor_VIIa
gptkb:Factor_Xa
|
|
gptkbp:alsoKnownAs
|
gptkb:Stuart–Prower_factor
|
|
gptkbp:cleavage
|
gptkb:Factor_Xa
|
|
gptkbp:cofactor
|
gptkb:vitamin_A
|
|
gptkbp:deficiencyCauses
|
bleeding disorder
|
|
gptkbp:discoveredBy
|
gptkb:E._G._Prower
gptkb:M._Stuart
gptkb:R._G._Macfarlane
|
|
gptkbp:domain
|
EGF-like domain
Gla domain
serine protease domain
|
|
gptkbp:EC_number
|
3.4.21.6
|
|
gptkbp:encodedBy
|
gptkb:F10_gene
|
|
gptkbp:firstDescribed
|
1956
|
|
gptkbp:function
|
blood coagulation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Factor X
|
|
gptkbp:inhibitedBy
|
gptkb:antithrombin
gptkb:tissue_factor_pathway_inhibitor
|
|
gptkbp:location
|
gptkb:chromosome_13
|
|
gptkbp:molecularWeight
|
59 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Factor_X_deficiency
|
|
gptkbp:OMIM
|
227600
|
|
gptkbp:partOf
|
coagulation cascade
|
|
gptkbp:PDB
|
1XKA
|
|
gptkbp:presentIn
|
gptkb:plasma
|
|
gptkbp:producedBy
|
liver
|
|
gptkbp:role
|
conversion of prothrombin to thrombin
|
|
gptkbp:structure
|
gptkb:serine_protease
|
|
gptkbp:synthesizedAs
|
zymogen
|
|
gptkbp:target
|
gptkb:warfarin
gptkb:rivaroxaban
gptkb:apixaban
gptkb:betrixaban
gptkb:edoxaban
gptkb:fondaparinux
gptkb:heparin
anticoagulant drugs
|
|
gptkbp:UniProtID
|
P00742
|
|
gptkbp:usedIn
|
diagnosis of coagulation disorders
|
|
gptkbp:bfsParent
|
gptkb:Age_of_Apocalypse
|
|
gptkbp:bfsLayer
|
5
|