Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:serine_protease
gptkb:enzyme |
| gptkbp:activated_from |
gptkb:Factor_X
|
| gptkbp:activatedBy |
gptkb:Factor_IXa
gptkb:Factor_VIIa tissue factor |
| gptkbp:actsOn |
prothrombin
|
| gptkbp:CASNumber |
9002-05-9
|
| gptkbp:cofactor |
gptkb:Factor_Va
|
| gptkbp:convertedTo |
prothrombin to thrombin
|
| gptkbp:EC_number |
3.4.21.6
|
| gptkbp:foundIn |
blood plasma
|
| gptkbp:gene |
gptkb:F10
|
| gptkbp:has_active_site |
serine residue
|
| https://www.w3.org/2000/01/rdf-schema#label |
Factor Xa
|
| gptkbp:inhibitedBy |
gptkb:rivaroxaban
gptkb:apixaban gptkb:betrixaban gptkb:edoxaban gptkb:fondaparinux gptkb:antithrombin_III direct oral anticoagulants |
| gptkbp:molecularWeight |
~45 kDa
|
| gptkbp:partOf |
coagulation cascade
|
| gptkbp:producedBy |
liver
|
| gptkbp:requires |
vitamin K for synthesis
|
| gptkbp:role |
blood coagulation
|
| gptkbp:structure |
heterodimer
|
| gptkbp:substrate |
cleaves after arginine residues
|
| gptkbp:target |
anticoagulant drugs
|
| gptkbp:UniProtID |
P00742
|
| gptkbp:bfsParent |
gptkb:Factor_X
|
| gptkbp:bfsLayer |
6
|