|
gptkbp:instanceOf
|
gptkb:protein
gptkb:serine_protease
|
|
gptkbp:activatedBy
|
gptkb:heparin
|
|
gptkbp:alternativeName
|
gptkb:ATIII
gptkb:SERPINC1
gptkb:antithrombin_III
|
|
gptkbp:category
|
acute phase protein
coagulation inhibitor
|
|
gptkbp:deficiencyCauses
|
thrombophilia
|
|
gptkbp:discoveredBy
|
gptkb:Armand_J._Quick
|
|
gptkbp:encodedBy
|
gptkb:SERPINC1_gene
|
|
gptkbp:foundIn
|
blood plasma
|
|
gptkbp:function
|
gptkb:anticoagulant
|
|
gptkbp:halfLife
|
2.4 days
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
antithrombin
|
|
gptkbp:inhibitedBy
|
gptkb:factor_IXa
gptkb:factor_Xa
gptkb:thrombin
gptkb:factor_XIIa
gptkb:factor_XIa
|
|
gptkbp:length
|
432 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q25.1
|
|
gptkbp:medicalUse
|
gptkb:antithrombin_concentrate
|
|
gptkbp:molecularWeight
|
58 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:hereditary_antithrombin_deficiency
|
|
gptkbp:OMIM
|
107300
|
|
gptkbp:PDB
|
2ANT
|
|
gptkbp:presentIn
|
vertebrates
|
|
gptkbp:producedBy
|
liver
|
|
gptkbp:structureType
|
gptkb:protein
|
|
gptkbp:UniProtID
|
P01008
|
|
gptkbp:bfsParent
|
gptkb:Factor_X
gptkb:Thrombin
gptkb:factor_IX
gptkb:thrombin
|
|
gptkbp:bfsLayer
|
6
|