|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD326
TACSTD1
|
|
gptkbp:antibodyTarget
|
gptkb:Ber-EP4
MOC-31
|
|
gptkbp:associatedWith
|
gptkb:congenital_tufting_enteropathy
various cancers
|
|
gptkbp:cleavage
|
gptkb:gamma-secretase
TACE/ADAM17
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:encodedBy
|
TACSTD1 gene
|
|
gptkbp:Entrez_Gene_ID
|
4072
|
|
gptkbp:expressedIn
|
epithelial tissues
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:fullName
|
gptkb:Epithelial_Cell_Adhesion_Molecule
|
|
gptkbp:function
|
cell differentiation
cell proliferation
cell signaling
cell adhesion
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:glycosylation
|
N-linked
|
|
gptkbp:HGNC_ID
|
HGNC:11529
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
EpCAM
|
|
gptkbp:interactsWith
|
gptkb:beta-catenin
gptkb:E-cadherin
claudins
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
cell migration
epithelial-mesenchymal transition
|
|
gptkbp:locatedOnChromosome
|
chromosome 2p21
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
~40 kDa
|
|
gptkbp:OMIM
|
185535
|
|
gptkbp:orthologIn
|
gptkb:mouse
right
|
|
gptkbp:overexpressedIn
|
carcinomas
|
|
gptkbp:PDB
|
4MZV
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:target
|
immunotherapy
monoclonal antibodies
|
|
gptkbp:transmembraneDomains
|
1
|
|
gptkbp:UniProtID
|
P16422
|
|
gptkbp:usedAs
|
cancer biomarker
|
|
gptkbp:usedIn
|
circulating tumor cell detection
diagnosis of epithelial tumors
prognosis of cancer
|
|
gptkbp:bfsParent
|
gptkb:EPCAM
|
|
gptkbp:bfsLayer
|
6
|