|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:CD326
TACSTD1
|
|
gptkbp:associatedWith
|
gptkb:Lynch_syndrome
gptkb:congenital_tufting_enteropathy
|
|
gptkbp:discoveredBy
|
L. Moldenhauer et al.
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:encodes
|
Epithelial cell adhesion molecule
|
|
gptkbp:Entrez_Gene_ID
|
4072
ENSG00000119888
|
|
gptkbp:expressedIn
|
tumor cells
epithelial tissues
fetal tissues
|
|
gptkbp:fullName
|
epithelial cell adhesion molecule
|
|
gptkbp:function
|
cell proliferation
differentiation
cell signaling
cell adhesion
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:3235
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
EPCAM
|
|
gptkbp:interactsWith
|
gptkb:beta-catenin
gptkb:E-cadherin
claudins
|
|
gptkbp:length
|
~11 kb
|
|
gptkbp:locatedOnChromosome
|
2p21
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
~40 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:hereditary_nonpolyposis_colorectal_cancer
intestinal epithelial dysplasia
|
|
gptkbp:numberOfExons
|
9
|
|
gptkbp:OMIM
|
185535
|
|
gptkbp:orthologInMouse
|
gptkb:EpCAM
|
|
gptkbp:product
|
type I transmembrane glycoprotein
|
|
gptkbp:regulates
|
transcriptional
epigenetic
|
|
gptkbp:target
|
immunotherapy
catumaxomab
edrecolomab
|
|
gptkbp:UniProtID
|
P16422
|
|
gptkbp:usedAsMarker
|
carcinomas
circulating tumor cells
|
|
gptkbp:usedIn
|
stem cell research
cancer diagnostics
liquid biopsy
immunohistochemistry
flow cytometry
cell sorting
|
|
gptkbp:bfsParent
|
gptkb:Lynch_syndrome
|
|
gptkbp:bfsLayer
|
5
|