|
gptkbp:instanceOf
|
gptkb:Ensembl_gene_ID
|
|
gptkbp:alias
|
gptkb:BRAF-1
gptkb:BRAF1
gptkb:NS7
gptkb:RAFB1
gptkb:B-RAF
|
|
gptkbp:associatedWith
|
gptkb:cardiofaciocutaneous_syndrome
gptkb:cancer
gptkb:Noonan_syndrome
gptkb:melanoma
colorectal cancer
|
|
gptkbp:encodes
|
gptkb:BRAF
|
|
gptkbp:function
|
protein kinase activity
MAP kinase activity
|
|
gptkbp:gene
|
gptkb:BRAF
|
|
gptkbp:geneType
|
protein_coding
|
|
gptkbp:hasTranscript
|
gptkb:ENST00000288602
gptkb:ENST00000496384
gptkb:ENST00000646891
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:1097
|
|
gptkbp:isOnReferenceGenome
|
gptkb:GRCh37
gptkb:GRCh38
|
|
gptkbp:isPartOfPathway
|
gptkb:RAS_signaling_pathway
gptkb:MAPK/ERK_pathway
|
|
gptkbp:locatedOnChromosome
|
gptkb:7q34
7
140719327
140924929
|
|
gptkbp:mutationAssociatedWith
|
gptkb:V600K
D594G
G469A
V600E
|
|
gptkbp:NCBI_Gene_ID
|
673
|
|
gptkbp:numberOfExons
|
18
|
|
gptkbp:OMIM
|
164757
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Braf
|
|
gptkbp:product
|
gptkb:B-Raf_proto-oncogene_serine/threonine-protein_kinase
|
|
gptkbp:proteinFamily
|
gptkb:RAF_family
|
|
gptkbp:strand
|
plus
|
|
gptkbp:targetOfDrug
|
gptkb:encorafenib
gptkb:dabrafenib
gptkb:sorafenib
gptkb:vemurafenib
|
|
gptkbp:UniProtID
|
gptkb:P15056
|
|
gptkbp:bfsParent
|
gptkb:MMP13
|
|
gptkbp:bfsLayer
|
7
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
ENSG00000137745
|