|
gptkbp:instanceOf
|
neurotransmitter
|
|
gptkbp:actsOn
|
Dopamine receptors
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
gptkb:Attention_deficit_hyperactivity_disorder
Schizophrenia
Depression
Addiction
|
|
gptkbp:biosynthesized_from
|
gptkb:Tyrosine
|
|
gptkbp:category
|
Catecholamine
Monoamine neurotransmitter
|
|
gptkbp:chemicalFormula
|
C8H11NO2
|
|
gptkbp:degradedBy
|
gptkb:Catechol-O-methyltransferase
gptkb:Monoamine_oxidase
|
|
gptkbp:discoveredBy
|
gptkb:George_Barger
gptkb:James_Ewens
|
|
gptkbp:discoveredIn
|
1910
|
|
gptkbp:foundIn
|
gptkb:Brain
gptkb:Central_nervous_system
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dopamine (in brain)
|
|
gptkbp:influenced
|
gptkb:Pleasure
gptkb:Sleep
emotion
movement
Cognition
Attention
Reinforcement learning
|
|
gptkbp:involvedIn
|
Learning
Motivation
Motor control
Mood regulation
Reward pathway
|
|
gptkbp:modulatedBy
|
gptkb:Cocaine
gptkb:MAO_inhibitors
gptkb:Amphetamines
gptkb:Levodopa
Drugs
Antipsychotics
Stimulants
COMT inhibitors
|
|
gptkbp:predecessor
|
gptkb:Norepinephrine
Epinephrine
|
|
gptkbp:producedBy
|
gptkb:Hypothalamus
gptkb:Substantia_nigra
gptkb:Ventral_tegmental_area
|
|
gptkbp:receptorTypes
|
gptkb:D1_receptor
gptkb:D2_receptor
gptkb:D3_receptor
gptkb:D4_receptor
gptkb:D5_receptor
|
|
gptkbp:regulates
|
Prolactin secretion
|
|
gptkbp:releaseYear
|
Exocytosis
|
|
gptkbp:reuptakeBy
|
gptkb:Dopamine_transporter
|
|
gptkbp:storage
|
Synaptic vesicles
|
|
gptkbp:transportation
|
gptkb:Dopamine_transporter
|
|
gptkbp:bfsParent
|
gptkb:Reward
|
|
gptkbp:bfsLayer
|
7
|