|
gptkbp:instanceOf
|
gptkb:G_protein-coupled_receptor
gptkb:dopamine_receptor
|
|
gptkbp:activatedBy
|
gptkb:adenylate_cyclase
|
|
gptkbp:alternativeName
|
gptkb:dopamine_receptor_D1
gptkb:D1R
gptkb:DRD1
|
|
gptkbp:binds
|
dopamine
|
|
gptkbp:coupledTo
|
gptkb:Gs_protein
|
|
gptkbp:discoveredIn
|
1978
|
|
gptkbp:encodedBy
|
DRD1 gene
|
|
gptkbp:enemyOf
|
gptkb:A-68930
gptkb:SCH23390
gptkb:SKF-38393
gptkb:ecopipam
fenoldopam
|
|
gptkbp:expressedIn
|
gptkb:striatum
gptkb:olfactory_bulb
gptkb:cerebellum
hippocampus
amygdala
limbic system
frontal cortex
|
|
gptkbp:foundIn
|
gptkb:kidney
heart
retina
central nervous system
vascular smooth muscle
|
|
gptkbp:HGNC_ID
|
HGNC:3021
|
|
gptkbp:improves
|
cAMP levels
|
|
gptkbp:involvedIn
|
gptkb:Parkinson's_disease
addiction
cognition
memory
schizophrenia
learning
hypertension
motor control
reward pathway
renal sodium excretion
|
|
gptkbp:locatedOnChromosome
|
chromosome 5q35.1
|
|
gptkbp:molecularWeight
|
49 kDa
|
|
gptkbp:OMIM
|
126449
|
|
gptkbp:regulates
|
blood pressure
renal function
behavioral responses
neuronal growth
|
|
gptkbp:structure
|
seven transmembrane domains
|
|
gptkbp:subspecies
|
dopamine receptor D1-like family
|
|
gptkbp:UniProtID
|
gptkb:P21728
|
|
gptkbp:bfsParent
|
gptkb:Dopamine_(in_brain)
gptkb:dopamine_receptor_family
gptkb:Dopamine_Receptor_D
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
D1 receptor
|