D1 receptor

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instanceOf gptkb:G_protein-coupled_receptor
dopamine receptor
gptkbp:activatedBy gptkb:adenylate_cyclase
gptkbp:alternativeName gptkb:dopamine_receptor_D1
gptkb:D1R
gptkb:DRD1
gptkbp:binds dopamine
gptkbp:coupledTo gptkb:Gs_protein
gptkbp:discoveredIn 1978
gptkbp:encodedBy DRD1 gene
gptkbp:enemyOf gptkb:A-68930
gptkb:SCH23390
gptkb:SKF-38393
gptkb:ecopipam
fenoldopam
gptkbp:expressedIn gptkb:striatum
gptkb:olfactory_bulb
gptkb:cerebellum
hippocampus
amygdala
limbic system
frontal cortex
gptkbp:foundIn gptkb:kidney
heart
retina
central nervous system
vascular smooth muscle
gptkbp:HGNC_ID HGNC:3021
https://www.w3.org/2000/01/rdf-schema#label D1 receptor
gptkbp:improves cAMP levels
gptkbp:involvedIn gptkb:Parkinson's_disease
addiction
cognition
memory
schizophrenia
learning
hypertension
motor control
reward pathway
renal sodium excretion
gptkbp:locatedOnChromosome chromosome 5q35.1
gptkbp:molecularWeight 49 kDa
gptkbp:OMIM 126449
gptkbp:regulates blood pressure
renal function
behavioral responses
neuronal growth
gptkbp:structure seven transmembrane domains
gptkbp:subspecies dopamine receptor D1-like family
gptkbp:UniProtID gptkb:P21728
gptkbp:bfsParent gptkb:Dopamine_(in_brain)
gptkb:D1-like_dopamine_receptor
gptkb:dopamine_receptor_family
gptkb:Dopamine_Receptor_D
gptkbp:bfsLayer 8