|
gptkbp:instanceOf
|
alkaloid
controlled substance
stimulant drug
|
|
gptkbp:addictive_potential
|
high
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:ATCCode
|
N01BA01
|
|
gptkbp:boilingPoint
|
187 °C (decomposes)
|
|
gptkbp:can_cause_death
|
yes
|
|
gptkbp:CASNumber
|
50-36-2
|
|
gptkbp:chemicalFormula
|
C17H21NO4
|
|
gptkbp:color
|
white
|
|
gptkbp:discoveredBy
|
gptkb:Friedrich_Gaedcke
|
|
gptkbp:discoveredIn
|
1855
|
|
gptkbp:eliminationHalfLife
|
0.7–1.5 hours
|
|
gptkbp:flavor
|
bitter
|
|
gptkbp:hasStreet
|
snow
blow
coke
crack
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cocaine
|
|
gptkbp:IUPACName
|
methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
|
|
gptkbp:legalStatus
|
gptkb:Class_A_(UK)
gptkb:List_I_(Canada)
gptkb:Schedule_II_(US)
|
|
gptkbp:main_metabolite
|
gptkb:benzoylecgonine
gptkb:ecgonine_methyl_ester
gptkb:norcocaine
|
|
gptkbp:mechanismOfAction
|
blocks reuptake of monoamines
|
|
gptkbp:medicalUse
|
local anesthetic
vasoconstrictor
|
|
gptkbp:meltingPoint
|
98 °C
|
|
gptkbp:MeSH_ID
|
D003041
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
303.353 g/mol
|
|
gptkbp:neurotransmitter
|
dopamine
norepinephrine
serotonin
|
|
gptkbp:origin
|
gptkb:Erythroxylum_coca
|
|
gptkbp:produces
|
coca leaves
|
|
gptkbp:PubChem_CID
|
gptkb:CHEBI:27958
gptkb:CHEMBL29997
gptkb:DB00907
446220
|
|
gptkbp:risk_of_overdose
|
yes
|
|
gptkbp:routeOfAdministration
|
oral
inhalation
intravenous
intranasal
|
|
gptkbp:schedule_under_UN_conventions
|
gptkb:Schedule_I
|
|
gptkbp:sideEffect
|
addiction
anxiety
hypertension
paranoia
seizures
mydriasis
tachycardia
|
|
gptkbp:solubility
|
1.8 g/L
|
|
gptkbp:UNII
|
U3C868Y870
|
|
gptkbp:used_in_medicine
|
yes
|
|
gptkbp:used_recreationally
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Eric_Clapton
gptkb:エリック・クラプトン
|
|
gptkbp:bfsLayer
|
5
|