|
gptkbp:instanceOf
|
hormone
neurotransmitter
|
|
gptkbp:actsOn
|
adrenergic receptors
|
|
gptkbp:administeredBy
|
intravenous infusion
|
|
gptkbp:ATCCode
|
C01CA03
|
|
gptkbp:biosynthesized_from
|
gptkb:tyrosine
|
|
gptkbp:CASNumber
|
51-41-2
|
|
gptkbp:category
|
monoamine neurotransmitter
sympathomimetic amine
catecholamine
vasopressor
|
|
gptkbp:chemicalFormula
|
C8H11NO3
|
|
gptkbp:color
|
white to off-white (as solid)
|
|
gptkbp:decommissioned
|
enzymatic degradation
reuptake
|
|
gptkbp:discoveredBy
|
gptkb:Ulf_von_Euler
|
|
gptkbp:discoveredIn
|
1946
|
|
gptkbp:foundIn
|
gptkb:locus_coeruleus
gptkb:adrenal_medulla
|
|
gptkbp:function
|
modulates mood
increases blood pressure
increases heart rate
modulates arousal
modulates attention
modulates stress response
triggers fight-or-flight response
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Norepinephrine
|
|
gptkbp:IUPACName
|
4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
|
|
gptkbp:meltingPoint
|
234–236 °C
|
|
gptkbp:MeSH_ID
|
D009638
|
|
gptkbp:metabolism
|
gptkb:monoamine_oxidase
catechol-O-methyltransferase
|
|
gptkbp:molecularWeight
|
169.18 g/mol
|
|
gptkbp:predecessor
|
dopamine
|
|
gptkbp:producedBy
|
sympathetic nervous system
|
|
gptkbp:PubChem_CID
|
439260
CHEBI:33569
DB00368
|
|
gptkbp:relatedTo
|
dopamine
serotonin
epinephrine
|
|
gptkbp:reuptakeBy
|
gptkb:norepinephrine_transporter
|
|
gptkbp:sideEffect
|
gptkb:arrhythmia
anxiety
headache
hypertension
|
|
gptkbp:solubility
|
soluble in water
|
|
gptkbp:storageVesicle
|
gptkb:synaptic_vesicle
|
|
gptkbp:synonym
|
gptkb:noradrenaline
|
|
gptkbp:UNII
|
X4W7ZR7023
|
|
gptkbp:usedAs
|
gptkb:drug
|
|
gptkbp:usedFor
|
septic shock
hypotension
|
|
gptkbp:bfsParent
|
gptkb:neurotransmitter
|
|
gptkbp:bfsLayer
|
5
|