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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeName
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gptkb:NEP
CD167a
RTK6
TYRO10
discoidin domain receptor family, member 1
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gptkbp:associatedWith
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gptkb:cancer
fibrosis
|
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gptkbp:biologicalProcess
|
signal transduction
cell migration
ATP binding
cell adhesion
protein kinase activity
extracellular matrix organization
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gptkbp:cellularComponent
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gptkb:plasma_membrane
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gptkbp:discoveredBy
|
Michael D. Schaller
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gptkbp:discoveredIn
|
1992
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gptkbp:encodedBy
|
DDR1 gene
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gptkbp:Entrez_Gene_ID
|
ENSG00000154589
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gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
liver
epithelial cells
breast tissue
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gptkbp:fullName
|
Discoidin domain receptor tyrosine kinase 1
|
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gptkbp:function
|
gptkb:receptor_tyrosine_kinase
collagen receptor
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gptkbp:gene
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gptkb:DDR1
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gptkbp:HGNC_ID
|
HGNC:2731
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DDR1
|
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gptkbp:inhibitedBy
|
gptkb:dasatinib
gptkb:imatinib
gptkb:nilotinib
7rh benzamide derivatives
|
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gptkbp:interactsWith
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gptkb:collagen_type_I
gptkb:collagen_type_IV
collagen type VI
collagen type VIII
|
|
gptkbp:locatedOnChromosome
|
chromosome 6p21.3
|
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gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:glioblastoma
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:orthologIn
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gptkb:Danio_rerio
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
2F6A
|
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gptkbp:phosphorylates
|
Y513
Y792
Y796
|
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gptkbp:UniProtID
|
Q08345
|
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gptkbp:bfsParent
|
gptkb:Tegra_1
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gptkbp:bfsLayer
|
6
|