|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:approvalYear
|
2004
|
|
gptkbp:ATCCode
|
gptkb:N06AX21
|
|
gptkbp:brand
|
gptkb:Cymbalta
Irenka
Yentreve
|
|
gptkbp:CASNumber
|
gptkb:136434-34-9
|
|
gptkbp:drugClass
|
antidepressant
norepinephrine reuptake inhibitor
|
|
gptkbp:hasBiologicalActivity
|
gptkb:CYP1A2
gptkb:CYP2C9
gptkb:CYP2C19
gptkb:CYP2D6
gptkb:CYP3A4
|
|
gptkbp:hasInChIKey
|
PTQIMFZVAZTVBL-UHFFFAOYSA-N
|
|
gptkbp:hasMolecularFormula
|
gptkb:C18H19NOS
|
|
gptkbp:hasSMILES
|
CNCCC1=CC=CC=C1OC2=CC=CC=C2S
|
|
gptkbp:hasUNII
|
O5TNM5N07U
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DB01202
|
|
gptkbp:indication
|
gptkb:generalized_anxiety_disorder
gptkb:major_depressive_disorder
fibromyalgia
chronic musculoskeletal pain
diabetic peripheral neuropathic pain
|
|
gptkbp:isApprovedDrug
|
true
|
|
gptkbp:legalStatus
|
expired
prescription only
|
|
gptkbp:manufacturer
|
gptkb:Eli_Lilly_and_Company
|
|
gptkbp:molecularWeight
|
297.42
|
|
gptkbp:name
|
gptkb:Duloxetine
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:DB01202
60835
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
constipation
dizziness
fatigue
insomnia
dry mouth
somnolence
decreased appetite
increased blood pressure
hyperhidrosis
|
|
gptkbp:status
|
true
|
|
gptkbp:target
|
gptkb:SLC6A12
gptkb:SLC6A13
gptkb:SLC6A14
gptkb:SLC6A15
gptkb:SLC6A16
gptkb:SLC6A17
gptkb:SLC6A18
gptkb:SLC6A19
gptkb:SLC6A20
gptkb:SLC6A4
gptkb:HTR3A
gptkb:HTR3B
gptkb:HTR3C
gptkb:HTR3D
gptkb:HTR3E
gptkb:SLC6A1
gptkb:SLC6A11
gptkb:SLC6A8
gptkb:SLC6A2
gptkb:SLC6A3
gptkb:SLC6A7
gptkb:SLC6A9
gptkb:HTR1B
HTR2A
HTR1A
HTR1D
HTR1E
HTR1F
HTR2B
HTR2C
HTR4
HTR5A
HTR6
HTR7
|
|
gptkbp:bfsParent
|
gptkb:levetiracetam
|
|
gptkbp:bfsLayer
|
7
|