Duloxetine

GPTKB entity

Statements (53)
Predicate Object
gptkbp:instance_of gptkb:drug
gptkbp:bfsLayer 4
gptkbp:bfsParent gptkb:GSK
gptkbp:activities inhibits norepinephrine reuptake
inhibits serotonin reuptake
gptkbp:affects weight changes
sexual dysfunction
increased blood pressure
serotonin syndrome risk
gptkbp:approves gptkb:2004
gptkb:FDA
gptkbp:brand gptkb:Cymbalta
Yentreve
gptkbp:category gptkb:C
gptkbp:clinical_trial Phase IV
Phase III
gptkbp:contraindication MAO inhibitors
severe liver impairment
uncontrolled narrow-angle glaucoma
gptkbp:developed_by gptkb:Eli_Lilly_and_Company
gptkbp:dosage_form 120 mg daily maximum
30 mg to 60 mg daily
https://www.w3.org/2000/01/rdf-schema#label Duloxetine
gptkbp:ingredients C18 H19 NOS
gptkbp:interacts_with gptkb:beer
anticoagulants
other antidepressants
NSAI Ds
gptkbp:is_available_on gptkb:beer
delayed-release capsule
gptkbp:is_used_for chronic pain
fibromyalgia
generalized anxiety disorder
major depressive disorder
gptkbp:lifespan 12 hours
gptkbp:marketed_as gptkb:legislation
gptkb:Australia
gptkb:United_States
gptkb:Native_American_tribe
gptkbp:metabolism liver
gptkbp:side_effect dizziness
fatigue
nausea
insomnia
constipation
dry mouth
sweating
gptkbp:symptoms dizziness
headache
nausea
irritability
insomnia
gptkbp:type_of 116539-59-4