Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cell cycle regulator |
| gptkbp:alternativeSplicing |
produces isoforms
|
| gptkbp:degradedBy |
gptkb:ubiquitin-proteasome_pathway
|
| gptkbp:discoveredIn |
1991
|
| gptkbp:encodedBy |
gptkb:CCNE1_gene
gptkb:CCNE2_gene |
| gptkbp:formsComplexWith |
gptkb:CDK2
|
| gptkbp:function |
regulates G1/S transition in cell cycle
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cyclin E
|
| gptkbp:inhibitedBy |
gptkb:p21
gptkb:p27 |
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:overexpressedIn |
gptkb:cancer
|
| gptkbp:phosphorylates |
gptkb:Rb_protein
gptkb:Ser384 gptkb:Thr62 |
| gptkbp:regulates |
gptkb:E2F_transcription_factors
|
| gptkbp:role |
DNA replication initiation
centrosome duplication |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:UniProtID |
gptkb:O96020_(CCNE2)
gptkb:P24864_(CCNE1) |
| gptkbp:bfsParent |
gptkb:WAF1_gene
|
| gptkbp:bfsLayer |
6
|