|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:abbreviation
|
gptkb:CB1
|
|
gptkbp:alternativeName
|
gptkb:CB1_receptor
gptkb:CNR1
gptkb:central_cannabinoid_receptor
|
|
gptkbp:binds
|
gptkb:tetrahydrocannabinol
gptkb:endocannabinoids
synthetic cannabinoids
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodedBy
|
gptkb:CNR1_gene
|
|
gptkbp:enemyOf
|
gptkb:tetrahydrocannabinol
gptkb:2-arachidonoylglycerol
gptkb:SR141716A
gptkb:anandamide
gptkb:rimonabant
|
|
gptkbp:Entrez_Gene_ID
|
1268
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
gastrointestinal tract
liver
adipose tissue
|
|
gptkbp:foundIn
|
central nervous system
peripheral nervous system
|
|
gptkbp:function
|
modulation of neurotransmitter release
|
|
gptkbp:HGNC_ID
|
2159
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cannabinoid receptor 1
|
|
gptkbp:involvedIn
|
memory
pain modulation
motor control
appetite regulation
mood regulation
reward pathways
|
|
gptkbp:locatedOn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:modulatedBy
|
gptkb:potassium_channels
cAMP levels
calcium channels
|
|
gptkbp:OMIM
|
114610
|
|
gptkbp:PDB
|
gptkb:5U09
gptkb:6N4B
5TGZ
6KQI
|
|
gptkbp:relatedTo
|
Cannabinoid receptor 2
|
|
gptkbp:structureType
|
seven transmembrane domains
|
|
gptkbp:target
|
gptkb:SR141716A
gptkb:rimonabant
|
|
gptkbp:UniProtID
|
gptkb:P21554
|
|
gptkbp:bfsParent
|
gptkb:CB1R
gptkb:CNR1_protein
gptkb:P32239
|
|
gptkbp:bfsLayer
|
8
|