|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CB1R
gptkb:cannabinoid_receptor_type_1
gptkb:CB1
|
|
gptkbp:associatedWith
|
gptkb:endocannabinoid_system
memory
pain modulation
psychiatric disorders
appetite regulation
neurological processes
|
|
gptkbp:biologicalProcess
|
modulates neurotransmitter release
activates MAP kinase pathway
affects appetite
affects memory
affects mood
affects pain sensation
influences motor control
inhibits adenylate cyclase activity
regulates synaptic plasticity
|
|
gptkbp:discoveredBy
|
gptkb:Matsuda_et_al.
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodes
|
gptkb:cannabinoid_receptor_1
|
|
gptkbp:Entrez_Gene_ID
|
1268
|
|
gptkbp:expressedIn
|
brain
central nervous system
peripheral tissues
|
|
gptkbp:HGNC_ID
|
2159
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CNR1 gene
|
|
gptkbp:length
|
472 amino acids
|
|
gptkbp:ligand
|
gptkb:tetrahydrocannabinol
gptkb:2-arachidonoylglycerol
gptkb:anandamide
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
6q14-q15
|
|
gptkbp:mutationAssociatedWith
|
gptkb:depression
addiction
schizophrenia
obesity
migraine
|
|
gptkbp:OMIM
|
114610
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Cnr1
|
|
gptkbp:product
|
gptkb:CB1_receptor
|
|
gptkbp:recipient
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:target
|
gptkb:rimonabant
synthetic cannabinoids
cannabinoid drugs
phytocannabinoids
|
|
gptkbp:UniProtID
|
gptkb:P21554
|
|
gptkbp:bfsParent
|
gptkb:CB1
|
|
gptkbp:bfsLayer
|
6
|