|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CB1_receptor
gptkb:Cannabinoid_receptor_1
|
|
gptkbp:associatedWith
|
memory
pain modulation
appetite regulation
mood regulation
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodedBy
|
gptkb:CNR1_gene
|
|
gptkbp:Entrez_Gene_ID
|
1268
|
|
gptkbp:expressedIn
|
brain
central nervous system
peripheral tissues
|
|
gptkbp:foundIn
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:function
|
gptkb:G_protein-coupled_receptor
binds endocannabinoids
binds phytocannabinoids
involved in neurotransmission
|
|
gptkbp:HGNC_ID
|
2159
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CNR1 protein
|
|
gptkbp:length
|
472
|
|
gptkbp:ligand
|
gptkb:THC
gptkb:2-arachidonoylglycerol
gptkb:anandamide
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6_(human)
|
|
gptkbp:molecularWeight
|
53 kDa
|
|
gptkbp:mutationAssociatedWith
|
addiction
obesity
psychiatric disorders
|
|
gptkbp:OMIM
|
114610
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:PDB
|
5TGZ
6KQI
|
|
gptkbp:postTranslationalModification
|
palmitoylation
glycosylation
|
|
gptkbp:relatedTo
|
gptkb:CNR2_protein
|
|
gptkbp:target
|
gptkb:rimonabant
synthetic cannabinoids
cannabinoid drugs
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:type
|
activates MAP kinase pathway
inhibits adenylate cyclase
|
|
gptkbp:UniProtID
|
gptkb:P21554
|
|
gptkbp:bfsParent
|
gptkb:cannabinoid_receptor_1
|
|
gptkbp:bfsLayer
|
7
|