|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:CCCTC-binding_factor
11-zinc finger protein
transcriptional repressor CTCF
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
intellectual disability
epigenetic regulation
genomic imprinting
chromatin looping
|
|
gptkbp:biologicalProcess
|
DNA binding
zinc finger protein
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
|
|
gptkbp:conservedIn
|
vertebrates
|
|
gptkbp:discoveredBy
|
gptkb:Gary_Felsenfeld
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000102974
|
|
gptkbp:fullName
|
gptkb:CCCTC-binding_factor
|
|
gptkbp:function
|
regulation of gene expression
transcriptional regulator
chromatin insulator
regulation of chromatin architecture
|
|
gptkbp:gene
|
gptkb:CTCF
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:13723
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CTCF protein
|
|
gptkbp:interactsWith
|
gptkb:RNA_polymerase_II
gptkb:cohesin_complex
YY1 protein
|
|
gptkbp:length
|
727
|
|
gptkbp:locatedOnChromosome
|
16q22.1
|
|
gptkbp:OMIM
|
604167
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
5YEL
5T0U
5TOU
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
poly(ADP-ribosyl)ation
|
|
gptkbp:regulates
|
gptkb:MYC_gene
gptkb:H19/IGF2_locus
gptkb:beta-globin_locus
gptkb:HOX_gene_clusters
gptkb:XIST_gene
imprinted genes
topologically associating domains (TADs)
enhancer-promoter interactions
|
|
gptkbp:requires
|
cell differentiation
embryonic development
genome organization
|
|
gptkbp:UniProtID
|
gptkb:P49711
|
|
gptkbp:bfsParent
|
gptkb:CTCF_binding_sites
gptkb:CTCFC_protein
|
|
gptkbp:bfsLayer
|
8
|