|
gptkbp:instanceOf
|
gptkb:protein
transcription factor
|
|
gptkbp:alias
|
11-zinc finger protein
transcriptional repressor CTCF
CCCTC-binding zinc finger protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cohesin_complex
intellectual disability
epigenetic regulation
|
|
gptkbp:biologicalProcess
|
regulation of gene expression
DNA binding
transcription factor activity
chromatin looping
genome organization
insulator activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
|
|
gptkbp:discoveredBy
|
gptkb:Gary_Felsenfeld
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:DNA_binding_motif
|
CCCTC
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000102974
10664
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:function
|
chromatin organization
transcriptional regulation
insulator protein
|
|
gptkbp:gene
|
gptkb:CTCF_gene
|
|
gptkbp:HGNC_ID
|
2511
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CCCTC-binding factor
|
|
gptkbp:length
|
727
|
|
gptkbp:locatedOnChromosome
|
16q22.1
|
|
gptkbp:molecularWeight
|
82 kDa
|
|
gptkbp:number_of_zinc_fingers
|
11
|
|
gptkbp:OMIM
|
604167
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
gptkb:Drosophila_melanogaster
|
|
gptkbp:postTranslationalModification
|
phosphorylation
poly(ADP-ribosyl)ation
SUMOylation
|
|
gptkbp:regulates
|
gptkb:X-chromosome_inactivation
imprinting of IGF2/H19 locus
TAD boundaries
enhancer-blocking activity
|
|
gptkbp:requires
|
embryonic development
genome stability
|
|
gptkbp:structure
|
zinc finger protein
|
|
gptkbp:symbol
|
gptkb:CTCF
|
|
gptkbp:UniProtID
|
gptkb:P49711
|
|
gptkbp:bfsParent
|
gptkb:CTCF
|
|
gptkbp:bfsLayer
|
8
|