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gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CBP
gptkb:KAT3A
|
|
gptkbp:amendedBy
|
histones
non-histone proteins
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Rubinstein-Taybi_syndrome
intellectual disability
|
|
gptkbp:binds
|
gptkb:CREB
gptkb:p53
transcription factors
nuclear receptors
|
|
gptkbp:encodedBy
|
CREBBP gene
|
|
gptkbp:Entrez_Gene_ID
|
1387
|
|
gptkbp:enzymeCommissionNumber
|
EC 2.3.1.48
|
|
gptkbp:firstDescribed
|
1993
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
histone acetyltransferase
transcription coactivator
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CREB binding protein
|
|
gptkbp:interactsWith
|
gptkb:EP300
gptkb:RNA_polymerase_II
gptkb:STAT_proteins
gptkb:BRCA1
gptkb:NF-κB
|
|
gptkbp:locale
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
16p13.3
|
|
gptkbp:molecularWeight
|
~265 kDa
|
|
gptkbp:orthologIn
|
present in many eukaryotes
|
|
gptkbp:phosphorylates
|
subject to phosphorylation
|
|
gptkbp:postTranslationalModification
|
ubiquitination
acetylation
|
|
gptkbp:regulates
|
apoptosis
DNA repair
gene expression
metabolism
immune response
cell cycle
|
|
gptkbp:requires
|
cell differentiation
embryonic development
memory formation
|
|
gptkbp:structure
|
contains HAT domain
contains KIX domain
contains bromodomain
contains TAZ domains
|
|
gptkbp:UniProtID
|
gptkb:Q92793
|
|
gptkbp:bfsParent
|
gptkb:CREBBP
|
|
gptkbp:bfsLayer
|
8
|