|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:HU-308
gptkb:JWH-133
|
|
gptkbp:alternativeName
|
gptkb:CB2_receptor
Cannabinoid receptor 2
|
|
gptkbp:associatedWith
|
gptkb:cancer
pain modulation
autoimmune diseases
neuroinflammation
|
|
gptkbp:compatibleWith
|
brain (in high levels)
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodedBy
|
gptkb:CNR2_gene
|
|
gptkbp:Entrez_Gene_ID
|
1269
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
gptkb:tonsils
gptkb:B_cells
gptkb:thymus
gptkb:microglia
spleen
macrophages
|
|
gptkbp:foundIn
|
humans
mice
rats
|
|
gptkbp:function
|
signal transduction
cannabinoid receptor activity
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CNR2 protein
|
|
gptkbp:inhibitedBy
|
gptkb:AM630
|
|
gptkbp:ligand
|
gptkb:endocannabinoids
synthetic cannabinoids
phytocannabinoids
|
|
gptkbp:locatedOnChromosome
|
human chromosome 1p36
|
|
gptkbp:location
|
gptkb:cell_membrane
immune system cells
|
|
gptkbp:memberOf
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:molecularWeight
|
~39 kDa
|
|
gptkbp:OMIM
|
605051
|
|
gptkbp:orthologIn
|
gptkb:fish
birds
amphibians
mammals
reptiles
|
|
gptkbp:phosphorylates
|
serine residues
threonine residues
|
|
gptkbp:relatedTo
|
gptkb:CB1_receptor
|
|
gptkbp:role
|
immune response
inflammation regulation
|
|
gptkbp:structure
|
seven transmembrane domains
|
|
gptkbp:target
|
therapeutic drugs
|
|
gptkbp:UniProtID
|
gptkb:P34972
|
|
gptkbp:bfsParent
|
gptkb:CNR1_protein
|
|
gptkbp:bfsLayer
|
8
|