|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:activatedBy
|
gptkb:endocannabinoids
synthetic cannabinoids
phytocannabinoids
|
|
gptkbp:alternativeName
|
gptkb:CNR2
gptkb:Cannabinoid_receptor_type_2
CB2
|
|
gptkbp:associatedWith
|
neuroprotection
modulation of immune response
pain regulation
anti-inflammatory effects
|
|
gptkbp:biologicalProcess
|
G protein-coupled receptor activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodedBy
|
gptkb:CNR2_gene
|
|
gptkbp:enemyOf
|
gptkb:AM-1241
gptkb:AM630
gptkb:HU-308
gptkb:JWH-133
gptkb:SR144528
gptkb:beta-caryophyllene
|
|
gptkbp:expressedIn
|
peripheral tissues
central nervous system (low levels)
|
|
gptkbp:foundIn
|
gptkb:tonsils
gptkb:B_cells
gptkb:T_cells
gptkb:thymus
gptkb:mast_cells
gptkb:microglia
spleen
bone marrow
peripheral nervous system
immune system
macrophages
gastrointestinal system
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CB2 receptor
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1p36
|
|
gptkbp:OMIM
|
605051
|
|
gptkbp:relatedTo
|
gptkb:CB1_receptor
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:targetOfDrug
|
neurodegenerative diseases
autoimmune diseases
inflammatory diseases
peripheral neuropathy
|
|
gptkbp:type
|
activates MAP kinase pathway
inhibits adenylyl cyclase
|
|
gptkbp:UniProtID
|
gptkb:P34972
|
|
gptkbp:bfsParent
|
gptkb:JWH_cannabinoids
gptkb:endocannabinoid_system
gptkb:CB2_receptor_(indirect)
gptkb:D8
gptkb:THC
|
|
gptkbp:bfsLayer
|
6
|