|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
CB2
cannabinoid receptor 2 (peripheral)
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodes
|
Cannabinoid receptor 2
|
|
gptkbp:Entrez_Gene_ID
|
1269
ENSG00000188822
|
|
gptkbp:expressedIn
|
gptkb:tonsils
gptkb:B_cells
gptkb:thymus
spleen
macrophages
immune cells
|
|
gptkbp:function
|
encodes a G protein-coupled receptor
involved in immune system modulation
|
|
gptkbp:HGNC_ID
|
2159
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CNR2 gene
|
|
gptkbp:length
|
360 amino acids
|
|
gptkbp:ligand
|
gptkb:endocannabinoids
synthetic cannabinoids
phytocannabinoids
|
|
gptkbp:locatedOnChromosome
|
gptkb:1p36.11
chromosome 1
|
|
gptkbp:locusType
|
gptkb:1p36.11
|
|
gptkbp:mutationAssociatedWith
|
gptkb:bone
autoimmune diseases
peripheral neuropathy
psychiatric disorders
|
|
gptkbp:OMIM
|
605051
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Cnr2
|
|
gptkbp:product
|
gptkb:CB2_receptor
gptkb:G_protein-coupled_receptor
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
cannabinoid receptor family
|
|
gptkbp:regulates
|
regulated by cytokines
regulated by immune activation
|
|
gptkbp:relatedTo
|
gptkb:endocannabinoid_system
inflammation
immune response
|
|
gptkbp:significance
|
target for pain management
target for anti-inflammatory drugs
potential target for neurodegenerative diseases
|
|
gptkbp:symbol
|
gptkb:CNR2
|
|
gptkbp:UniProtID
|
gptkb:P34972
|
|
gptkbp:bfsParent
|
gptkb:CB2_receptor
gptkb:cannabinoid_receptors
|
|
gptkbp:bfsLayer
|
7
|