Statements (32)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
gptkbp:alias |
gptkb:p15INK4b
|
gptkbp:associatedWith |
gptkb:cancer
tumor suppression |
gptkbp:biologicalProcess |
cell cycle arrest
negative regulation of cell proliferation cyclin-dependent protein serine/threonine kinase inhibitor activity |
gptkbp:encodes |
p15 protein
|
gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000147889
1030 |
gptkbp:expressedIn |
various tissues
|
gptkbp:fullName |
gptkb:Cyclin-dependent_kinase_inhibitor_2B
|
gptkbp:function |
inhibits cyclin-dependent kinases 4 and 6
|
gptkbp:HGNC_ID |
HGNC:1788
|
https://www.w3.org/2000/01/rdf-schema#label |
CDKN2B (p15INK4b)
|
gptkbp:inhibitedBy |
gptkb:CDK4
gptkb:CDK6 |
gptkbp:locatedOnChromosome |
gptkb:9p21
|
gptkbp:mutationAssociatedWith |
leukemia
melanoma glioma |
gptkbp:OMIM |
600431
|
gptkbp:orthologIn |
gptkb:mouse
right |
gptkbp:regulates |
cell cycle G1 phase
|
gptkbp:relatedTo |
gptkb:CDKN2A
gptkb:CDKN2C |
gptkbp:symbol |
gptkb:CDKN2B
|
gptkbp:UniProtID |
P42772
|
gptkbp:bfsParent |
gptkb:CDK4_gene
|
gptkbp:bfsLayer |
8
|