|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:cell_division_control_protein_2_homolog
p34CDC2
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
cell division
DNA damage response
G2/M transition of mitotic cell cycle
|
|
gptkbp:cofactor
|
Mg2+
|
|
gptkbp:discoveredBy
|
gptkb:Paul_Nurse
|
|
gptkbp:discoveredIn
|
1976
|
|
gptkbp:EC_number
|
2.7.11.22
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000170312
983
|
|
gptkbp:enzymeClassification
|
serine/threonine-protein kinase
|
|
gptkbp:fullName
|
gptkb:Cyclin-dependent_kinase_1
|
|
gptkbp:function
|
cell cycle regulation
mitosis regulation
|
|
gptkbp:gene
|
gptkb:CDK1
|
|
gptkbp:GO_term
|
GO:0004693
GO:0000086
GO:0000280
|
|
gptkbp:HGNC_ID
|
HGNC:1722
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CDK1 protein
|
|
gptkbp:inhibitedBy
|
Flavopiridol
Purvalanol A
RO-3306
|
|
gptkbp:interactsWith
|
gptkb:CDC25C
gptkb:Cyclin_B1
gptkb:Cyclin_A
gptkb:p21
gptkb:p53
Wee1
|
|
gptkbp:KEGGID
|
gptkb:hsa:983
|
|
gptkbp:length
|
297 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 10q21.2
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
34 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Cdc28 (yeast)
Cdk1 (mouse)
|
|
gptkbp:PDB
|
4YC3
|
|
gptkbp:phosphorylates
|
Tyr15
Thr14
Thr161
|
|
gptkbp:Reactome
|
gptkb:R-HSA-69231
|
|
gptkbp:RefSeq
|
NP_001777.1
|
|
gptkbp:UniProtID
|
gptkb:P06493
|
|
gptkbp:bfsParent
|
gptkb:CDC28A
|
|
gptkbp:bfsLayer
|
7
|