hereditary diffuse gastric cancer
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
hereditary cancer syndrome |
| gptkbp:alsoKnownAs |
gptkb:HDGC
|
| gptkbp:associatedWith |
gptkb:signet_ring_cell_carcinoma
|
| gptkbp:diagnosedBy |
genetic testing
|
| gptkbp:firstDescribed |
1998
|
| https://www.w3.org/2000/01/rdf-schema#label |
hereditary diffuse gastric cancer
|
| gptkbp:ICD-10_code |
gptkb:C16
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:managedBy |
increased cancer surveillance
prophylactic gastrectomy |
| gptkbp:mutationAssociatedWith |
gptkb:CDH1_gene
|
| gptkbp:OMIM |
137215
|
| gptkbp:prevalence |
rare
|
| gptkbp:riskFactor |
gptkb:diffuse_gastric_cancer
gptkb:lobular_breast_cancer |
| gptkbp:riskOfCancerByAge80 |
up to 56% for women
up to 70% for men |
| gptkbp:symptom |
nausea
vomiting abdominal pain weight loss |
| gptkbp:bfsParent |
gptkb:Gastric_cancer
gptkb:E-cadherin |
| gptkbp:bfsLayer |
6
|